RT Journal Article
SR Electronic
T1 Historical Review of Glasses Used for Parenteral Packaging
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 279
OP 296
DO 10.5731/pdajpst.2016.007377
VO 71
IS 4
A1 Robert A. Schaut
A1 W. Porter Weeks
YR 2017
UL http://journal.pda.org/content/71/4/279.abstract
AB Glass has long been used for packaging precious liquids, in particular pharmaceuticals. Its unique combination of hermeticity, transparency, strength, and chemical durability make it the optimal material for such an important role. Today's life-saving drugs are stored in borosilicate glasses, which evolved from applications in microscope optics and thermometers. As the glass compositions improved, so did the methods used to shape them and the tests used to characterize them. While all of these advances improved the quality of the glass container and its ability to protect the contents, problems still exist such as delamination, cracks, and glass particulates. In addition to these issues, we review new developments in glass composition development, performance, and testing in the 21st century.