TABLE II

Correlation of He-Leak Values to Risk of Microbial Failure per Kirsch et al.a

Hole Diameter (µ)He-Leak (cm3/s @ STP)−log (He-Leak)Microbial Ingress Rate (%)
21.0 × 10–33.070
0.72.0 × 10–43.765
0.49.0 × 10–65.011
---6 × 10–65.28–10
0.32.0 × 10–65.77
0.22.2 × 10–76.60
0.11.0 × 10–77.00
  • a This table is a reproduction based upon data reported. A value of 6 × 10–6 cm3/s–corresponding to a microbial ingress rate <10%–was considered acceptable.