Test Article Composition | Treatment Time (Min) | LRVb |
---|---|---|
M. orale100 mM glycine pH 3.8 | 5 | 0.5 ± 0.1 |
60 | 1.9 ± 0.6 | |
M. orale100 mM glycine pH 3.5 | 5 | 0.9 ± 0.3 |
60 | 3.3 ± 0.4 | |
M. orale100 mM acetate pH 3.8 | 5 | 0.7 ± 0.2 |
60 | 2.2 ± 0.5 | |
M. orale100 mM acetate pH 3.5 | 5 | 1.2 ± 0.3 |
60 | 4.1 ± 0.5 |
↵a Antibody-containing eluate was titrated to pH 3.5 or 3.8, spiked with M. orale and incubated for 60 min. Samples were taken at time 0 min (sample load concentration), 5 min, and 60 min, then tittered.
b LRV is log reduction value.