TABLE I

Amebocyte Lysate-based Kits

LAL Kit VendorKit NameAssay FormatAmebocyte Lysate Source
LonzaKinetic QCLChromogenic, onset timeLimulus polyphemus
QCL-100Chromogenic, end point
PYROGENTGel clot, end point
PYROGENT PlusGel clot, end point
PYROGENT-5000Turbidimetric, kinetic
FujiFilm-WakoaPYROSTAR ES-FTurbidimetric, onset time or Gel clot, end pointLimulus polyphemus
Limulus Color KY TestChromogenic, onset time
Charles River LaboratoriesEndochrome-KChromogenic, kineticLimulus polyphemus
KTA and KTA2bTurbidimetric, kinetic
Gel-Clot Endotoxin TestGel clot, end point
Endosafe Rapid LALChromogenic, end point
Seikagaku/ACCPyrochromeChromogenic, onset timeLimulus polyphemus
PyrosateGel clot, end point
Chromo-LALChromogenic, kinetic
PyrotellGel clot, end point
Pyrotell-TTurbidimetric, end point
Endospecy ES-50MChromogenic, rateTachypleus tridentatus

  • ↵a LAL is co-lyophilized with a beta-glucan blocker.

  • ↵b KTA2 is a rapid test.