Calculated Interfacial Tension Values between Excipients and Silicone Oil at 90 days and 23°C As Fitted to Hua–Rosen Theory
| Starting Solutions | + 0.06 wt. %PS 80a | + 0.06 wt.% PS 80 + 5% Mannitol | + 0.06 wt.% PS 80 + 150 mM NaCl |
|---|---|---|---|
| 20 mM Acetate buffer, pH 4.5 | 4.99 | 3.80 | 6.20 |
| 20 mM Acetate buffer, pH 5.5 | 4.97 | 4.73 | 6.41 |
| 20 mM Histidine buffer, pH 5.5 | 3.75 | 4.01 | 6.26 |
| 20 mM Citrate buffer, pH 5.5 | 4.85 | 4.93 | 6.11 |
↵a PS 80, polysorbate 80.