Silicone Oil Layer Thickness, Total Weight, and Water Contact Angle for Syringes Exposed to Different Buffer Solutions and Water at 40°C for 12 Weeks
| Acetate pH = 4.5 | Acetate pH = 5.5 | Water for Injection | |
|---|---|---|---|
| Silicone layer thickness (nm) | 246.5 ± 4.9 | 265.5 ± 27.6 | 247.0 ± 8.5 |
| Total silicone weight (µg) | 262.5 ± 2.1 | 284.5 ± 29.0 | 264.5 ± 9.2 |
| Water contact angle (°) | 108.1 ± 0.5 | 100.1 ± 3.5 | 100.1 ± 0.6 |