TABLE III

Interfacial Tension (IFT) of Water and Select Excipients against Silicone Oil at Equilibrium

IFT (mN/m) at Equilibrium
Water26.23
PS 80a 0.06%5.69
Mannitol 5%27.36
NaCl 150 mM26.21
20 mM Acetate buffer, pH 4.524.70
20 mM Acetate buffer, pH 5.525.50
20 mM Histidine buffer, pH 5.525.66
20 mM Citrate buffer, pH 5.526.78

  • ↵a PS 80, polysorbate 80.