Headspace Carbon Dioxide Partial Pressure in Sample Vials with Microwires at the Stopper-Seal Interface, Both Before (T0) and After (T1) a Container Closure Integrity (CCI) Test That Was Conducted 1 Week After Sample Preparation. Values Are the Averages of Five Consecutive Measurements on Each Vial
| Nominal Wire Size [μm] | Fill | Headspace Carbon Dioxide Partial Pressure [Torr] | Number of Leaking Vials Detecteda | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T1 | |||||||||
| Mean | StDev | Min | Max | Mean | StDev | Min | Max | |||
| 41 | 5 mL1 mg/mLBSA in PBS | 0 | 0.0 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0/5 |
| 64 | 0 | 0.1 | 0 | 0 | 369 | 321.9 | 4 | 676 | 5/5 | |
| 80 | 0 | 0.0 | 0 | 0 | 441 | 352.6 | 0 | 803 | 4/5 | |
| NCb | Empty | 1 | 0.1 | 1 | 1 | 1 | 0.1 | 1 | 1 | 0/3 |
| GPCc | 1 | 0.2 | 0 | 1 | 707 | 3.3 | 703 | 709 | 3/3 | |