Headspace Carbon Dioxide Partial Pressure in Sample Vials with Laser-Drilled Defects, Both Before (T0) and After (T1) a Container Closure Integrity (CCI) Test that was Conducted 1 Week After Sample Preparation. Values Are the Averages of Five Consecutive Measurements on Each Vial
| Nominal Wire Size [μm] | Fill | Headspace Carbon Dioxide Partial Pressure [Torr] | Number of Leaking Vials Detecteda | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T1 | |||||||||
| Mean | StDev | Min | Max | Mean | StDev | Min | Max | |||
| 2 | 5 mL of 1 mg/mL BSA in PBS | 0 | 0.1 | 0 | 1 | 0 | 0.1 | 0 | 1 | 0/10 |
| 5 | 0 | 0.1 | 0 | 1 | 88 | 87.3 | 0 | 235 | 7/10 | |
| 10 | 0 | 0.1 | 0 | 1 | 426 | 311.8 | 66 | 956 | 10/10 | |
| NCb | Empty | 1 | 0.1 | 1 | 1 | 1 | 0.1 | 1 | 1 | 0/3 |
| GPCc | 1 | 0.2 | 1 | 1 | 707 | 3.3 | 703 | 709 | 3/3 | |