Design of Experiment Sets to Study the Impact of Excipients on Syringe Functional Performances
| Sample | Buffer | pH | Surfactant | Tonicity |
|---|---|---|---|---|
| 1 | Acetate | Low | PS80 | Mannitol |
| 2 | Acetate | Low | PS80 | NaCl |
| 3 | Acetate | Low | P188 | Mannitol |
| 4 | Acetate | Low | P188 | NaCl |
| 5 | Acetate | High | PS80 | Mannitol |
| 6 | Acetate | High | PS80 | NaCl |
| 7 | Acetate | High | P188 | Mannitol |
| 8 | Acetate | High | P188 | NaCl |
| 9 | Histidine | Low | PS80 | Mannitol |
| 10 | Histidine | Low | PS80 | NaCl |
| 11 | Histidine | Low | P188 | Mannitol |
| 12 | Histidine | Low | P188 | NaCl |
| 13 | Histidine | High | PS80 | Mannitol |
| 14 | Histidine | High | PS80 | NaCl |
| 15 | Histidine | High | P188 | Mannitol |
| 16 | Histidine | High | P188 | NaCl |
| 17 | Citrate | Low | PS80 | Mannitol |
| 18 | Citrate | Low | PS80 | NaCl |
| 19 | Citrate | Low | P188 | Mannitol |
| 20 | Citrate | Low | P188 | NaCl |
| 21 | Citrate | High | PS80 | Mannitol |
| 22 | Citrate | High | PS80 | NaCl |
| 23 | Citrate | High | P188 | Mannitol |
| 24 | Citrate | High | P188 | NaCl |