MuLV, PrV, and Reo-3: Detectable and <4.0 LRV and Replicated Parameters Summarya
| Model Virus | Number of Runs | mAb or non-mAb | Filtration Volume (L/m2) | Fraction Tested by PCR | Fraction of Total Runs | Fraction of Total Runs Excluding PCR |
|---|---|---|---|---|---|---|
| MuLV | 8 | Both | 7–214 | 2/8 (25%) | 8/1516 (0.53%) | 6/1516 (0.40%) |
| PrV | 6 | mAb | Not Reported | 4/6 (67%) | 6/385 (1.56%) | 2/385 (0.52%) |
| Reo-3 | 0 | NA | NA | NA | 0 | 0 |
| Total | 14 | NA | NA | 6/14 (42.9%) | 14/2311 (0.61%) | 8/2311 (0.35%) |
↵a Summary of runs with detectable virus, < 4.0 LRV clearance, and replicate run with additional parameters including therapeutic type, volume, and assay type. mAb = monoclonal antibody; MuLV = murine leukemia virus; PCR = polymerase chain reaction; PrV = pseudorabies virus; Reo-3 = reovirus type 3.