TABLE II

MuLV, PrV, and Reo-3 Virus Filtration Database Summary of Runs Evaluateda

Model VirusSize Range (nm)Total RunsNon-Detectable Results (%)Detectable Results (%)Detectable and≥4.0 LRVDetectable and <4.0 LRVDetectable and <4.0 LRV and replicated
MuLV80–11015161488 (98.15%)28 (1.85%)15 (0.99%)13 (0.86%)8 (0.53%)
PrV120–200385373 (96.88%)12 (3.12%)6 (1.56%)6 (1.56%)6 (1.56%)
Reo-360-80410388 (94.63%)22 (5.37%)20 (4.88%)2 (0.49%)0
TotalNA23112249 (97.31%)62 (2.68%)41 (1.77%)21 (0.91%)14 (0.61%)
  • a Summary of individual and total runs examined in this study including model virus, virus size, number of runs, and the viral clearance classification as defined within study. The percentage provided in parentheses represents percentage of Total Runs listed in the third column. LRV = log reduction value; MuLV = murine leukemia virus; PrV = pseudorabies virus; Reo-3 = reovirus type 3.