TABLE II

LLNA Potency Classification

LLNA EC3 (μg/cm2)Potency Classification
<100Strong
100–1,000Moderate
1,000–10,000Weak
>10,000Extremely Weak
NCaNonsensitizer
  • EC3, concentration expected to give a 3-fold stimulation of lymph node cell proliferation; LLNA, local lymph node assay; NC, not calculated.

  • a No positive response is obtained at any concentration tested; therefore, an EC3 value cannot be calculated. (Table from Gerberick et al. [21]).