Average Flow Effective Diameter and Flow Rate for Microwire Defects Created at the Stopper–Seal Interface Using a Crimp Pressure of 24 Psi for Both Vial Types (Glass or Plastic). N Represents the Number of Samples the Statistics Are Based on. NC Refers to the Negative Controls (Unmodified Vials)
| Vial | Wire size (µm) | Flow Effective Diameter (µm) | Flow Rate (sccs) | N | ||
|---|---|---|---|---|---|---|
| Mean | StDev | Mean | StDev | |||
| Glass | NC | 0.1 | 0.02 | 1.6E-06 | 5.68E-07 | 23 |
| 15 | 0.8 | 0.17 | 8.5E-05 | 3.57E-05 | 9 | |
| 20 | 0.4 | 0.04 | 2.5E-05 | 4.84E-06 | 3 | |
| 41 | 3.2 | 0.92 | 1.6E-03 | 8.97E-04 | 12 | |
| 64 | 8.3 | 1.52 | 1.0E-02 | 3.64E-03 | 12 | |
| 80 | 12.9 | 2.85 | 2.5E-02 | 1.03E-02 | 12 | |
| Plastic | NC | 0.2 | 0.03 | 8.7E-06 | 1.95E-06 | 23 |
| 15 | 0.5 | 0.14 | 4.1E-05 | 1.95E-05 | 6 | |
| 20 | 0.6 | 0.08 | 4.8E-05 | 1.36E-05 | 3 | |
| 41 | 2.6 | 0.67 | 1.1E-03 | 5.11E-04 | 12 | |
| 64 | 7.4 | 2.85 | 9.0E-03 | 8.87E-03 | 12 | |
| 80 | 10.2 | 2.47 | 1.6E-02 | 8.23E-03 | 12 | |