Antimicrobial Preservatives
| Excipient | Frequency | Range | Example |
|---|---|---|---|
| Benzalkonium chloride | 1 | 0.02% w/v | Celestone Soluspan® (Schering) 0.02% w/v |
| Benzethonium chloride | 4 | 0.01% | Benadryl® (Parke-Davis) 0.01% w/v |
| Benzyl alcohol | 90 | 0.75–5% | Dimenhydrinate Injection, USP (APP Pharmaceuticals) 5% |
| Chlorbutanol | 19 | 0.25–0.5% | Codine phosphate (Wyeth-Ayerst) 0.5% |
| m-Cresol | 13 | 0.1–0.315% | Humalog® (Lilly) 0.315% |
| Myristyl gamma-picolinium chloride | 2 | 0.0195–0.169% w/v | Depo-Provera® (Pharmacia-Upjohn) 0.169% w/v |
| Paraben methyl | 55 | 0.05–0.18% | Inapsine® (Janssen) 0.18% w/v |
| Paraben propyl | 45 | 0.005–0.1% | Xylocaine w/Epinephrine (Astra) 0.1% w/v |
| Phenol | 55 | 0.15–0.5% | Calcimar® (Rhone-Poulanc) 0.5% w/v |
| 2-Phenoxyethanol | 4 | 0.50% | Havrix® (SmithKline Beecham) 0.50% w/v |
| Phenyl mercuric nitrate | 3 | 0.001% | Antivenin® (Wyeth-Ayerst) 0.001% |
| Thimerosal | 50 | 0.003–0.012% | Atgam® (Pharmacia-Upjohn) 0.01% |