Japanese Pharmaceutical Excipients
Name | Uses | Administration Route |
---|---|---|
Aluminum chloride | Potentiating agent | IM, SC |
Aluminum hydroxide | Adsorbent | IM, SC |
Anhydrous sodium pyrophosphate | Dispersing agent, Isotonicity, Stabilizer | IV, IM, intraspinal |
Calcium disodium edetate | Stabilizer | IV, SC, intra-arterial, intraspinal, other |
Calcium D-saccharate | Stabilizer | IV |
Creatinine | Buffering agent, Stabilizer | IV, IM, intracutaneous, SC, other injection |
Cresol | Preservative | IV, IM, SC |
L-Cystine | Stabilizer | IV |
Cysteine hydrochloride | Antioxidant, Stabilizer | IM, IV |
Dibasic sodium citrate | Buffering agent, Vehicle | IV |
Diethanolamine | Buffer, Solubilizer, Stabilizer | IV |
N, N-Dimethylacetamide | Solvent | IV |
Disodium hydrogen phosphate, Anhydrous | Buffering agent, pH adjustment | IV, SC, IM, other injection |
Ethyl oleate | Solvent | IM, intracutaneous |
Ethylurea | Solubilizing agent | IM, IV |
Ferric chloride | Stabilizer | IV |
Gentisylethanolamide | Antiseptic | IV |
N-hydroxyethyl lactamide solution | Solubilizing agent | IV |
Inositol | Stabilizer, Vehicle | IV, IM |
L-Lysine-L-glutamate | Solubilizing agent, Stabilizer | IV |
Magnesium gluconate | Stabilizer | IV |
Maleic acid | Buffering agent, pH adjustment, Stabilizer | IM |
Maleic anhydride | Solubilizer, Stabilizer | IV |
Methanesulfonic acid | pH adjustment | IM, SC |
DL-Methionine | Stabilizer | IM, intra-arterial, SC, intracutaneous |
Monoethanol amine | Buffer agent, pH adjustment, Solubilizer, Stabilizer | IV |
Monopotassium L-glutamate monohydrate | Preservative, Stabilizer | SC |
Oleic acid and purified oleic acid | Dispersing agent, Solvent | IV |
Oleyl alcohol | IV | |
Phosphoric acid | Buffer agent, Isotonicity, pH adjustment, Solubilizing agent, Stabilizer | IV, IM, SC |
Polyoxyethylene castor oil (average added molar ethylene oxide is ∼35) | Dispersing agent, Emulsifying agent, Solubilizing agent, Stabilizer, Surfactant, Suspending agent, Vehicle | IV |
Polyoxyethylene hydrogenated castor oil 50 | Dispersing agent, Emulsifying agent, Solubilizing agent | IM, IV |
Polyoxyethylene hydrogenated castor oil 60 | Dispersing agent, Emulsifying agent, Solubilizing agent | SC, IM, IV, intraspinal |
Polyoxyethylene[160] polyoxypropylene [30] glycol | Dispersing agent, Emulsifying agent, Solubilizer, Stabilizer, Suspending agent, Vehicle, Surfactant, Wetting agent | IV |
Polysorbate 20 | Dispersing agent, Emulsifying agent, Solubilizer, Surfactant, Stabilizer, Suspending agent, Vehicle, Wetting agent | IV, SC |
Potassium pyrosulfite | Stabilizer | IV |
Sodium acetyl tryptophan | Stabilizer | IV, SC |
Sodium caprylate | Stabilizer | IV, SC |
Sodium chondroitin sulfate | Stabilizer | IV |
Sodium desoxycholate | Solubilizing agent | Intracutaneous, IV, intraspinal |
Sodium dihydrogen phosphate anhydrous | Buffer agent, Isotonicity, pH adjustment, Stabilizer | IV, IM, SC |
Sodium dihydrogen phosphate dihydrate | Buffer agent, Isotonicity, pH adjustment, Stabilizer | IM, IV, intra-arterial, SC, intracutaneous, intraspinal, other injection |
Sodium formaldehydesulfoxylate | Stabilizer | IV, IM |
Sodium metasulfobenzoate | Stabilizer | IV, IM, other injection |
Sodium sulfite | Antioxidant, Stabilizer | IV |
Sodium thioglycolate | Antioxidant, Stabilizer | IV, IM, SC |
Sodium thiomalate | IM | |
Stannous chloride | Reducing agent | IV |
Succinic acid | Buffering agent, pH adjustment | IV |
Sulfuric acid | Buffering agent, pH adjustment | IM, IV, intra-arterial |
alpha-Thioglycerol | Antioxidant | IV, IM, SC |
Thioglycolic acid | Solubilizing agent, Stabilizer | IV, IM, SC |
Tribasic sodium phosphate | Buffering agent, pH adjustment | IV, IM, SC |
Triethanolamine | Buffer, pH adjuster, Solubilizing agent, Stabilizer | IV |
Purified yolk lecithin | Emulsifier | IV |
Zinc acetate | Stabilizer | SC |
IM = intramuscular.
IV = intravenous.
SC = subcutaneous.