TABLE II

Dissolution Characteristics, Zinc Stearate

pHAnalyte Concentration, mg/L
PreparedMeasuredCaZnStearatePalmitate
Low pH, 0.05 M sodium phosphate buffer, 0.15 g salt per100 mL of solution
2.53.00.142910.11<0.05
3.04.40.20137<0.05<0.05
3.54.9<0.0519.30.06<0.05
4.05.3<0.056.6<0.05<0.05
4.55.5<0.053.8<0.05<0.05
Intermediate pH, 0.05 M potassium phosphate buffer, 0.15 g salt per 100 mL of solution
5.05.50.704.30.05<0.05
5.55.80.762.80.05<0.05
6.06.10.591.9<0.05<0.05
6.56.50.570.50<0.05<0.05
7.07.00.271.0<0.05<0.05
7.57.50.260.33<0.05<0.05
High pH, 0.025 M borate (sodium borate decihydrate) buffer, 0.5 g salt per 100 mL of solution
8.08.10.180.41<0.05<0.05
8.58.60.220.070.05<0.05
9.09.00.350.08<0.05<0.05
9.59.40.170.020.130.10
10.09.90.120.040.680.28
10.510.30.070.051.850.94
11.010.60.090.051.300.97