TABLE III

Dissolution Characteristics, Stearic Acid

pHAnalyte Concentration, mg/L
PreparedMeasuredCaZnStearatePalmitate
Low pH, 0.05 M sodium phosphate buffer, 0.15 g salt per100 mL of solution
2.52.8<0.010.050.14<0.05
3.03.1<0.01<0.010.19<0.05
3.53.6<0.01<0.01<0.05<0.05
4.04.1<0.010.03<0.05<0.05
4.54.7<0.010.04<0.05<0.05
Intermediate pH, 0.05 M potassium phosphate buffer, 0.15 g salt per100 mL of solution
5.05.10.090.020.10<0.05
5.55.50.100.05<0.05<0.05
6.06.00.070.02<0.05<0.05
6.56.50.070.020.45<0.05
7.07.00.070.010.90<0.05
7.57.50.040.010.44<0.05
High pH, 0.025 M borate (sodium borate decihydrate) buffer, 0.5 g salt per 100 mL of solution
8.07.90.03<0.010.31<0.05
8.58.50.01<0.010.35<0.05
9.09.00.270.020.53<0.05
9.59.30.07<0.010.31<0.05
10.09.80.02<0.010.37<0.05
10.510.10.03<0.010.23<0.05
11.010.3<0.01<0.010.09<0.05