TABLE I

General Categories and Examples of Novel Cell Substrates

CategoryCell Substrate
Naturally-occurring
    Mammalian tumorigenic and tumor-derived cell linesMDCK, A549, HeLa
    Avian cell lines and embryonic stem cellsEBx
    Insects and Insect cellsMosquitoes, Caterpillars (Bombyx mori);
Cell lines from Drosophila, Mosquito, Caterpillar (Spodoptera frugiperda: Sf-9, Sf-21, and Trichoplusia ni: Hi-5)
    Plants and plant cellsFungi, Algae, Carrot, Mushrooms, Tobacco
    BacteriaE. coli
Genetically-engineered
    Transgenic animalGoat
    Telomerase-established cell line with Ad5 complementationHER96
    Ad5-complementation cell lines293, PER.C6
    Packaging cell linesRetrovirus-based; Adenovirus-based
    Stable transfectantsCHO cell-expressed proteins