Table I

Mathematical Notations Used in This Paper

NotationInterpretation
y1The response for the test sample preparation
y2The response for the standard sample preparation
xThe concentration or dilution
f1(x)The dose-response curve for the test sample
f2(x)The dose-response curve for the standard sample
a1, b1The true intercept and the slope for the test sample
a2, b2The true intercept and the slope for the standard sample
ρThe true relative potency
ε1The residual error for the test sample
ε2The residual error for the standard sample
δiThe mean difference of log(y1) − log(y2) at dose/dilution level xi
σ2The residual variance
IThe number of concentration or dilution levels
JThe number of replicates at each concentration/dilution level
CA constant