TABLE I

Overview of Virus Spike Preparations Studied

Virus NameAbbr.FamilySize (nm)GenomeEnvelopeSources
Murine minute virusMMVParvoviridae18–26ssDNANoa, b, d, e
Murine leukemia virusMuLVRetroviridae80–110ssRNAYesa, b, d
PoliovirusPolPicornaviridae22–30ssRNANoa1, a2
Porcine parvovirusPPVParvoviridae18–26ssDNANoa, b, c, d, e
Pseudorabies virusPRVHerpesviridae120–200dsDNAYesa, d
Reovirus type 3Reo-3Reoviridae60–80dsRNANod1, d2
  • Viruses chosen for study are commonly-used model viruses in the biotech industry (4) and range by physicochemical features such as size (diameter), genome type, and presence or absence of envelope. A total of 18 preparations were characterized in this study and originated from one of up to five sources. Abbr., abbreviation of virus name commonly used in the field.