Value	Severity
1	Negligible: Has no potential to have an adverse effect on identity, strength, quality, purity or potency of a drug product
2	Minor: Has minimal potential to have an adverse effect on identity, strength, quality, purity or potency of a drug product
3	Moderate: Has moderate potential to have an adverse effect on identity, strength, quality, purity or potency of a drug product
4	Major: Has a substantial potential to have an adverse effect on identity, strength, quality, purity or potency of a drug product

Value	Frequency
1	Highly unlikely: The probability of the event occurring is so low that it can be assumed that the event will not occur
2	Unlikely: Event not expected to occur, but theoretically possible
3	Likely: Event may occur and/or has occurred in the past
4	Highly likely: Event expected to occur

Value	Detectability
1	Readily detectable: Will be detected
2	May be detectable: May be detected
3	Not detectable: No mechanism for detection