System Suitability Requirements
| Parameter | Criteria |
|---|---|
| Wavelength calibration or detector tuning | Must successfully calibrate or tune |
| Lowest quantity determinable | Not more than lowest qualified standard concentration (typically 0.05 μg/mL) |
| Correlation coefficient for standard curve | r ≥ 0.995 |
| Standard percent error, for recovery of standards | NMT 30% @ ≤0.5 mg/L NMT 10 % @ >0.5 mg/L |
| Laboratory control (LC) sample, analyzed at the beginning, end, and periodically the throughout run | Recovery of 100 ± 20% |
| Supplemented sample (SS) recovery | Recovery of 100 ± 30% |
| %RSD on replicate measurement for working standard and sample solutions with analyte concentrations greater than 1 mg/L | NMT 10% |
| Internal standard ratio (blank) to sample response | 0.7–1.3 |
NMT = not more than.