Summary of Fluid Characterizations and Peristaltic Pump Parameters with Optimal Filling Profile (No Dripping) of Liquid Formulations from Stainless Steel Nozzles of Different Sizes
| Characterization/Parameter | Water (with 0.04% Tween 20) | mAb A (180 mg/mL) | BSA (370 mg/mL) |
|---|---|---|---|
| Viscosity at 20 °C (cP) | 1 | 9 | 25 |
| Contact angle on stainless steel surface (°) | 53.6 ± 1.0 | 75.2 ± 1.8 | 86.1 ± 1.8 |
| Contact angle on glass surface (°) | 32.6 ± 1.5 | 25.4 ± 1.1 | 40.3 ± 2.4 |
| Pump velocity (rpm) | 200 | 200 | 200 |
| Pump acceleration (no unit) | 4 | 50 | 125 |
| SB setting | |||
| 1.5 mm stainless steel nozzle | 1 | 5 | 10 |
| 2.0 mm stainless steel nozzle | 1 | 2 | 3 |
| 2.5 mm stainless steel nozzle | 1 | 2 | 2 |