MMV and MuLV Clearance by Membrane Filtration: Merck, Sharp and Dohme Study Using Fractionation and Inline Filtration
| Load | Initial Clearance Studies Using Fractionation and Inline Filtration | ||
|---|---|---|---|
| Log Reduction Values (log10) in Each Fraction | |||
| 0 to 750 g/L | 750 to 1500 g/L | 1500 to 2500 g/L | |
| mAb A + MuLV | >4.6 | 3.7 | 3.0 |
| mAb A + MMV | 5.1 | 0.4 | 0.0 |
| Buffer + MuLV | 3.8 | 1.8 | 1.3 |