Table I

Typical Viruses Used in Viral Clearance Studies

Virus NameAbbrev.FamilySize (nm)EnvelopeGenomeShapeChem. Resist.
Murine minute virusMMVParvoviridae18–26NossDNAIcosa-hedralV. high
Murine leukemia virusMuLVRetroviridae80–110YesssRNASphericalLow
Pseudorabies virusPRVHerpesviridae120–200YesdsDNASphericalMed
Reovirus type 3Reo-3Reoviridae60–80NodsRNASphericalMed
PoliovirusPolPicornaviridae22–30NossRNAIcosa-hedralMed
Porcine parvovirusPPVParvoviridae18–26NossDNAIcosa-hedralV. high
Simian vacuolating virus 40SV40Polyomaviridae40–50NodsDNAIcosa-hedralV. high
Bovine virus diarrheaBVDVFlaviviridae50–70YesssRNAPleo/SpherLow