Impact of Load Material on XMuLV LRV in the Protein A Elution Pool
| Protein A Load Material | XMuLV LRV of Elution Pool (qPCR) | |
|---|---|---|
| MAb 1 | MAb 2 | |
| XMuLV in equilibration buffer* | 4.01 | |
| XMuLV + HCCF | 2.78 | 1.91 |
| XMuLV + purified Drug Substance | 2.12 | 2.67 |
| XMuLV + HCCF with MAb removed* | 5.07 | 4.61 |
↵* As no product was present, collected pool during elution phase was the same volume as a product pool.