Table II

Kinetics of XMULV Inactivation in HCCF at 5 °C as a Function of LDAO Concentration

LDAO Content (%, w/v)Time (min)LRV
MAb 10.012152.01
120a2.52
0.02315≥3.08
120a≥4.15
0.03515≥2.84
120a≥3.90
0.06915≥3.03
120a≥4.10
0.13815≥2.90
120a≥3.97
  • a Large volume of sample was tested to decrease limit of detection of the assay.