Summary of XMuLV and Suid Herpes Viral Inactivation Kinetics with LDAO for 3 MAbs and 1 Fc Fusion Protein at 5 °C
| Time (min) | LRV | |
|---|---|---|
| XMuLV | 5 | ≥2.9 to ≥3.5 |
| 15 | ≥2.9 to ≥3.5 | |
| 60 | ≥2.9 to ≥3.5 | |
| 120 | ≥3.9a to ≥4.6a | |
| SuHV-1 | 5 | ≥2.3 to ≥5.1 |
| 15 | ≥2.3 to 4.8 | |
| 60 | ≥2.3 to ≥5.1 | |
| 120 | ≥3.4a to ≥6.6a |
↵a Large volume of sample was tested to decrease limit of detection of the assay.
b Log reduction range across all four molecules.