Virus Clearance Results for Bind/Elute AEX for Two Product Proteins, Which Require Different NaCl Levels To Elute the Product Protein from the AEX Column
Virus | Assay | Logs Virus Clearance, Product 1 Elution with 150 mM NaCl, pH 8 | Logs Virus Clearance, Product 2 Elution with 400 mM NaCl pH 8 |
---|---|---|---|
Baculovirus | qPCR | 5.5 | 1.2 |
PPV | Infectivity | 3.7 | <1 |
MMV | qPCR | 1.3 | 1.7 |