Time for mAb Formulation Drying (Nozzle Clogging) in 2.0 mm Nozzles of Various Materials in Response to Suck-back Settings
| Suck-back Setting | Nozzle Material | ||||
|---|---|---|---|---|---|
| Stainless Steel | Glass | Polypropylene | Teflon®-coated Stainless Steel | Silicone-coated Glass | |
| 0 | Significant drying after 30 min (thin fill stream) | Clogged after 15 min | Clogged after 60 min | Droplet on tip of nozzle had dried after 3 h, but no clogging (was easily dispensed) | Significant drying after 1 h (thin fill stream) |
| 1 | Clogged after 30 min | Clogged after 30 min | No drying after 3 h | Drying but no clogging after 3 h (still capable of dispensing) | Drying but no clogging after 3 h (still capable of dispensing) |
| 2 | Clogged after 60 min | Clogged after 15 min | Drying but no clogging after 3 h (still capable of dispensing) | Drying but no clogging after 3 h (still capable of dispensing) | Drying but no clogging after 3 h (still capable of dispensing) |
| 3 | Clogged after 30 min | Clogged after 30 min | No drying after 3 h | No drying after 3 h | No drying after 3 h |