Table 2-3

Detergent Inactivation in Clarified Harvest vs Lysed Cell Supernatant

Test SampleLog Reduction Value (Log10TCID50)
0.5 min13 min2
mAb 1Clarified harvest≥4.88≥5.36
Lysed cell supernatant5.19≥5.35
mAb 2Clarified harvest≥5.13≥5.61
Lysed cell supernatant≥4.385.17

  • ↵1 4 mL volume tested.

  • ↵2 12 mL volume tested.