SuHV-1 Low pH Virus Inactivation at 15–26 °C
| mAb | Buffer | Protein Conc. (g/L) | Titrant | pH | No Detected Virus at Time (min) | Step LRF (log10) |
|---|---|---|---|---|---|---|
| 5 | 100 mM Gly, 200 mM Ace | 4–6 | Acetic Acid | 3.81 | 15−30 | ≥5.1, ≥5.6 |
| 2 | 75 mM Ace | 5.7–5.9 | Acetic Acid | 3.81 | 5 | ≥5.6, ≥4.9 |
| 7 | 100 mM Gly, 200 mM Ace | 7.1 | Acetic Acid | 3.88–3.90 | 15 | ≥6.5, ≥6.8 |
Gly: Glycine, Ace: Acetate.