Viral Filtration with DPRP Using Viral Filter A
| mAb | Pressure (psi) | Viral Load (log10 TCID50/mL) | LRF Pool 1 (before pause) | LRF Pool 2 (after pause) | LRF Pooled Filtrate | Total Virus Breakthrough |
|---|---|---|---|---|---|---|
| A | 14.2 | 4.7 | ≥3.9 | ≥4.5 | ≥3.7 | ≤1.5 × 103 |
| B | 14.2 | 4.7 | 4.09 | ≥4.5 | >4.0 | 9.7 × 102 |
| A | 14.2 | 5.3 | ≥4.5 | 4.5 | >4.2 | 7.0 × 103 |
| B | 14.2 | 5.7 | ≥4.9 | 4.7 | >4.4 | 1.2 × 104 |
| A | 14.2 | 6.4 | ≥5.2 | 4.4 | >4.3 | 2.1 × 105 |
| B | 14.2 | 6.6 | ≥5.7 | 4.5 | >4.5 | 1.2 × 105 |