Viral Filtration without DPRP Using Viral Filter A
| mAb | Pressure (psi) | Viral Load (log10 TCID50/mL) | LRF Pool 1 (250 mL) | LRF Pool 2 (50 mL) | LRF Pooled Filtrate | Total Virus Breakthrough |
|---|---|---|---|---|---|---|
| A | 14.2 | 4.4 | ≥3.6 | ≥4.2 | ≥3.5 | ≤1.5 × 103 |
| B | 14.2 | 4.3 | ≥3.47 | ≥4.1 | ≥3.3 | ≤1.5 × 103 |
| A | 14.2 | 5.4 | ≥4.6 | ≥5.2 | ≥4.5 | ≤1.5 × 103 |
| B | 14.2 | 5.8 | ≥4.9 | ≥5.6 | ≥4.9 | ≤1.5 × 103 |
| A | 14.2 | 6.2 | ≥5.35 | ≥6.0 | ≥5.2 | ≤1.5 × 103 |
| B | 14.2 | 6.4 | ≥5.6 | ≥6.2 | ≥5.5 | ≤1.5 × 103 |