Protein D Recovery, Aggregation, and Degradation after Storage in Prefillable Syringes for 14 Months
| Sample | Soluble Protein Recovered (SE-HPLC) | Aggregates (Percent of Soluble Protein) | Degradation (Percent of Soluble Protein) |
|---|---|---|---|
| Control | 100.00 ± 0.74 | 2.25 ± 0.0.06 | 0.00 |
| Glass—5 °C | 99.10 ± 1.78 | 2.27 ± 0.05 | 0.00 |
| CZA—5 °C | 101.67 ± 0.94 | 2.42 ± 0.05 | 0.00 |
| CZE—5 °C | 101.05 ± 0.70 | 2.36 ± 0.13 | 0.00 |
| Glass—25 °C | 100.78 ± 2.06 | 5.58 ± 0.10 | 2.33 ± 0.32 |
| CZA—25 °C | 100.70 ± 0.60 | 6.66 ± 0.11 | 3.15 ± 0.24 |
| CZE—25 °C | 100.91 ± 0.38 | 6.55 ± 0.11 | 3.49 ± 0.14 |