Comparison of WLI, 3D-LSM, and Combined WLI+LAI for the Characterization of the Silicone Oil Layer Thickness in Empty Glass Syringes
| WLI | 3D-LSM | WLI+LAI | |
|---|---|---|---|
| Thickness range | 80–4000 nm | >10 nm | 20–4000 nm |
| Layer imaging | − | + | − |
| Single measurement time | ∼4 s | ∼60 s | ∼15 s |
| Radial thickness mapping | ++ | + | ++ |
| Longitudinal thickness mapping | ++ | + | ++ |
| Sample preparation | + | − | + |