TABLE III

Comparison of CCI Results Obtained by Headspace Analysis (Performed at Room Temperature, After 1 Day of Storage in Dry Ice) and by the Helium-Leakage Test (ThermCCI) Measured Directly at −60°C (After 1 Day of Storage in Dry Ice) in 2 mL Vials with Serum Stoppers

Storage Conditions: StaticCO2 Headspace (Number of Leaking Vials/Total Vials)Helium-Leak @ −60°C (Number of Leaking Vials/Total Vials)
RTa0/102/10
−75°C (*)b0/103/10
Storage Conditions: DynamicCO2 Headspace (Number of Leaking Vials/Total Vials)Helium-Leak @ −60°C (Number of Leaking Vials/Total Vials)
RT0/102/10
−75°C (*)0/102/10

  • ↵a RT: room temperature.

  • ↵b Dry ice; Shaded cells show 1%–100% leaking vials (leak).