TABLE III

Effectiveness of Resin Regeneration Procedure in Inactivating/Removing Retroviruses

Sample	Total Log₁₀ TCID₅₀ or PFU of Indicated Sample
	Case I				Case II				Case III
	First Run^{^a}		Second Run		First Run^{^a}		Second Run		First Run^{^a}		Second Run
	Exp. A	Exp. B	Exp. A	Exp. B	Exp. A	Exp. B	Exp. A	Exp. B	Exp. A	Exp. B	Exp. A	Exp. B
Spiked Load	7.67	7.50	N/A	N/A	7.17	7.42	N/A	N/A	7.36	7.06	N/A	N/A
Flow-through	7.55	7.20	≤3.53	≤3.53	7.18	7.30	≤2.51	≤2.51	6.58	7.33	≤3.91	≤3.91
Combined Wash	6.30	5.87	≤2.09	≤2.09	5.75	5.87	≤1.58	≤1.58	5.53	5.25	≤3.10	≤3.08
Front Side	≤3.43	3.19	≤1.79	≤1.79	≤2.65	≤2.65	≤0.84	≤0.84	≤4.05	≤3.05	≤1.72	≤1.70
Mainstream	≤2.00	≤2.00	≤2.02	≤2.02	≤3.38	≤3.35	≤1.48	≤1.66	≤3.26	≤3.26	≤1.53	≤1.53
Back Side	≤3.36	≤3.36	≤3.55	≤3.55	≤3.48	≤3.51	≤1.72	≤1.57	≤3.42	≤3.42	≤2.09	≤2.08
Hold Control	Exp. A = 7.67 and Exp. B = 7.58				Exp. A = 6.54 and Exp. B = 7.04				Exp. A = 6.90 and Exp. B = 7.13