TABLE II

Model Viruses Used in Spiking Studies

FamilyVirus NameIsoeletric PointSize (nm)EnvelopeGenomeShapeUsed for PA/AEX
FlaviviridaeBovine viral diarrhea virusNot reported50–70YesRNASphericalAEX
HerpesviridaeHerpes simplex virus5.5–6.3a120–200YesDNASphericalPA/AEX
Suid HerpesvirusNot reported120–200YesDNASphericalPA/AEX
ReoviridaeReovirus type 33.8b60–80NoRNASphericalPA/AEX
ParvoviridaeAdeno-associated virus∼6c18–24NoDNAIcosahedralPA/ AEX
Murine parvovirus6.2d18–24NoDNAIcosahedralPA/AEX
Porcine parvovirus5.1–6.0e18–24NoDNAIcosahedralPA/AEX
PicornaviridaeEncephalomyocarditis virusStrain dependentf25–30NoRNAIcosahedralPA/AEX
Hepatitis A virus2.8f27–32NoRNAIcosahedralPA
PolyomaviridaeSimian virus 405.4d40–50NoDNAIcosahedralPA/AEX
RetroviridaeAmphotropic murine leukemia virus6.0g80–130YesRNASphericalPA/AEX
Xenotropic murine leukemia virus5.8d80–110YesRNASphericalPA/AEX

  • ↵a Reference 23.

  • ↵b Reference 24.

  • ↵c Reference 25.

  • ↵d Reference 19.

  • ↵e Reference 26.

  • ↵f Reference 27.

  • ↵g Reference 28.