Blood clearance and organ deposition of intravenously administered colloidal particles. The effects of particle size, nature and shape
References (21)
Solid Colloidal drug delivery systems: tianoparticles
Int. J. Pharm.
(1981)- et al.
Distribution of radiolabeled subvisible microspheres after intravenous administration to Beagle dogs
J. Pharm. Sci.
(1978) Measurement of gastric blood flow with radioactive microspheres
J. Appl. Physiol.
(1975)- et al.
Autoradiographic studies of distribution in the liver of 198Au and 99mTc-sulphur colloids
Radiology
(1973) - et al.
Pulmonary perfusion imaging: active toxicity and safety factors as a function of particle size
J. Nucl. Med.
(1978) - et al.
The relevance of Pharmacopoeial Particulate Matter Limit tests
Drug Dev. Commun.
(1976) - et al.
Radionuclide imaging in pharmaceutical, physiological and pharmacological research
Clin. Phys. Physiol. Meas.
(1981) - et al.
A radiation induced bonding of iodine at the surface of uniform polystyrene particles
Radiat. Res.
(1974) - et al.
Cellulose microspheres as a sustained release system for parenteral administration
Int. J. Pharm.
(1982)
Cited by (243)
Challenges, opportunities, and future prospects of polysaccharide-based nanoparticles for colon targeting: A comprehensive review
2023, Carbohydrate Polymer Technologies and ApplicationsComparative study between a gravity-based and peristaltic pump for intravenous infusion with respect to the generation of proteinaceous microparticles
2023, International Journal of PharmaceuticsImpact of mechanical stress on flexible tubing used for biomedical applications: Characterization of the damages and impact on the patient's health
2022, Journal of the Mechanical Behavior of Biomedical MaterialsCitation Excerpt :There is an impact of their size and their shape on the risk encountered by the patient (Ilium et al., 1982); for example, smaller glass beads produced greater pulmonary dysfunction, may be due to higher systemic effect (Kusaka et al., 2014). The distribution of particles in the body is moreover size dependent: some authors showed the larger particles were retained in the lungs (12 μm) but the smaller ones were retained in organs (liver and spleen) (Ilium et al., 1982; Kanke et al., 1980). Pulmonary vessel can be obstructed by large fibers and this was responsible of death using rabbit as a model.
Simultaneous infusion of two incompatible antibiotics: Impact of the choice of infusion device and concomitant simulated fluid volume support on the particulate load and the drug mass flow rates
2022, International Journal of PharmaceuticsCitation Excerpt :The American Society of Health-System Pharmacists defines drug incompatibility as the formation of a physical or visual compatibility and/or decomposition of one or more components by more than 10% in less than 24 h under the specified conditions, (Trissel, 2018). The main risk associated with drug incompatibility is partial or complete catheter blockage (Benlabed et al., 2019; Boehne et al., 2013; Jack et al., 2012; Lehr et al., 2002; McNearney et al., 2003; Sasse et al., 2015), which in turn leads to delayed infusion, drug loss, the formation of toxic components, the deposition of particles in key organs (kidney, liver, and lungs) and particle-induced mechanical damage to blood vessels and systemic inflammatory response syndromes (Ilium et al., 1982; Jack et al., 2012). The present in vitro study replicated one of the intravenous infusion set-ups used in the critical care unit at Saint-Antoine Hospital (Paris, France), with the combined infusion of amikacin, vancomycin and piperacillin/tazobactam through the medial lumen of a three-lumen catheter.
Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity
2022, Nanomedicine: Nanotechnology, Biology, and Medicine