Evaluation of the chemical compatibility of plastic contact materials and pharmaceutical products; safety considerations related to extractables and leachables

J Pharm Sci. 2007 Oct;96(10):2566-81. doi: 10.1002/jps.20984.

Abstract

A review is provided on the general topic of the compatibility of plastic materials with pharmaceutical products, with specific emphasis on the safety aspects associated with extractables and leachables related to such plastic materials.

Publication types

  • Review

MeSH terms

  • Consumer Product Safety* / legislation & jurisprudence
  • Drug Contamination / prevention & control*
  • Drug Packaging*
  • Europe
  • Guidelines as Topic
  • Pharmaceutical Preparations / chemistry*
  • Plastics / chemistry*
  • Solubility
  • Technology, Pharmaceutical / legislation & jurisprudence
  • Technology, Pharmaceutical / methods*
  • United States
  • United States Food and Drug Administration

Substances

  • Pharmaceutical Preparations
  • Plastics