Abstract
A cell-associated bacteriocinlike substance with an approximate molecular weight of 78,000 was isolated from an oral isolate of Propionibacterium acnes. The substance was bacteriostatic and was active against both gram-positive and gram-negative anaerobes. Lysozyme inhibited the activity of the bacteriocinlike substance at low ionic strength.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacteriocins / analysis
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Bacteriocins / antagonists & inhibitors
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Bacteriocins / biosynthesis*
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Bacteriocins / pharmacology
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Dental Plaque / microbiology*
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Gram-Negative Anaerobic Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Humans
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Pronase / pharmacology
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Propionibacterium acnes / metabolism*
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Trypsin / pharmacology
Substances
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Bacteriocins
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Trypsin
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Pronase