Negative correlation of n-octanol/water partition coefficient and transport of some guanine derivatives through rat jejunum in vitro

Pharm Res. 1998 Mar;15(3):499-501. doi: 10.1023/a:1011901104421.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • 1-Octanol / chemistry
  • Acyclovir / analogs & derivatives*
  • Acyclovir / chemistry
  • Acyclovir / metabolism*
  • Animals
  • Antiviral Agents / metabolism*
  • Biological Transport
  • Diffusion
  • In Vitro Techniques
  • Jejunum / metabolism*
  • Prodrugs / metabolism*
  • Rats
  • Rats, Wistar
  • Water / chemistry

Substances

  • Antiviral Agents
  • Prodrugs
  • Water
  • desciclovir
  • 1-Octanol
  • Acyclovir