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Page 1
When will we have a clone? An industry perspective on the typical CLD timeline.
Clarke H, Mayer-Bartschmid A, Zheng C, Masterjohn E, Patel F, Moffat M, Wei Q, Liu R, Emmins R, Fischer S, Rieder S, Kelly T. Clarke H, et al. Among authors: emmins r. Biotechnol Prog. 2024 Mar 13:e3449. doi: 10.1002/btpr.3449. Online ahead of print. Biotechnol Prog. 2024. PMID: 38477447 Review.
Advancing Biologics Development Programs with Legacy Cell Lines: Advantages and Limitations of Genetic Testing for Addressing Clonality Concerns Prior to Availability of Late Stage Process and Product Consistency Data.
Wu P, Hartman T, Almond L, Stevens J, Thrift J, Ojha J, Alves C, Shaw D, Laird MW, Emmins R, Zhu Y, Liu R, Du Z, Koehler R, Jostock T, Anderson K, Campbell C, Clarke H. Wu P, et al. Among authors: emmins r. PDA J Pharm Sci Technol. 2020 Mar-Apr;74(2):264-274. doi: 10.5731/pdajpst.2018.009316. Epub 2019 Sep 13. PDA J Pharm Sci Technol. 2020. PMID: 31519780 Review.
A widespread family of bacterial cell wall assembly proteins.
Kawai Y, Marles-Wright J, Cleverley RM, Emmins R, Ishikawa S, Kuwano M, Heinz N, Bui NK, Hoyland CN, Ogasawara N, Lewis RJ, Vollmer W, Daniel RA, Errington J. Kawai Y, et al. Among authors: emmins r. EMBO J. 2011 Sep 30;30(24):4931-41. doi: 10.1038/emboj.2011.358. EMBO J. 2011. PMID: 21964069 Free PMC article.
Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development.
Zingaro K, Shaw D, Carson J, Mayer-Bartschmid A, Bender C, Alves C, Mcvey D, Qian NX, Wei Q, Laird MW, Zhu Y, Emmins R, Follit JA, Porter A, Racher AJ, Milne S, Carubelli I, Du Z, Khatri A, Failly M, Broly H, Lee F, Reeser M, Spidel J, Anderson K, Demaria C, Di-Carlo J, Gill J, Lundquist A, Kumar SR, Gill T. Zingaro K, et al. Among authors: emmins r. PDA J Pharm Sci Technol. 2018 Jul-Aug;72(4):438-450. doi: 10.5731/pdajpst.2018.008789. Epub 2018 Apr 18. PDA J Pharm Sci Technol. 2018. PMID: 29669815
Specificity of human anti-variable heavy (VH ) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor-α receptor 1.
Cordy JC, Morley PJ, Wright TJ, Birchler MA, Lewis AP, Emmins R, Chen YZ, Powley WM, Bareille PJ, Wilson R, Tonkyn J, Bayliffe AI, Lazaar AL. Cordy JC, et al. Among authors: emmins r. Clin Exp Immunol. 2015 Nov;182(2):139-48. doi: 10.1111/cei.12680. Epub 2015 Sep 11. Clin Exp Immunol. 2015. PMID: 26178412 Free PMC article. Clinical Trial.