Purpose Food production is among the highest human environmental impacting activities.
Agriculture itself accounts for 70–85 % of the water footprint and 30 % of world greenhouse …

… of a notch in … notch. The distribution of plastic-elastic strain in the yielded region can be
represented by an inverted pile-up of dislocations. The results are related to the problem of notch-…

Regulatory DNA elements such as enhancers, silencers and insulators are embedded in
metazoan genomes, and they control gene expression during development. Although they fulfil …

… at a notch root. The relation also holds when localized plastic yielding occurs at the notch
root. It … can easily be used for a simulation of the local strain-stress history near a notch root. …

Recent studies of genome-wide chromatin interactions have revealed that the human genome
is partitioned into many self-associating topological domains. The boundary sequences …

The effect of trichostatin A (TSA)-induced histone acetylation on the interphase chromatin
structure was visualized in vivo with a HeLa cell line stably expressing histone H2A, which was …

Ubiquitous calpains (μ- and m-calpain) have been repeatedly implicated in apoptosis, but
the underlying mechanism(s) remain(s) to be elucidated. We examined ionomycin-induced …

Although methods for light microscopy of chromatin are well established, there are no
quantitative data for nucleosome concentrations in vivo. To establish such a method we used a …

The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain
multiple variable (V H ), diversity (D H ), joining (J H ) and constant (C H ) coding elements. …

This study reports on the modeling and numerical computation of drug transport from a
laminated system into the skin. The model is based on the diffusion equation, on partitioning of …