The techniques of iontophoresis and electroporation can be used to enhance topical and
transdermal drug delivery. Iontophoresis applies a small low voltage (typically 10 V or less) …

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago
there were only 19 biotechology medicines on the market. Currently there are more than 100, …

Iontophoretic drug delivery implies the delivery of ionic (charged) drugs into the body by the
use of electric current. The technique is not new and has been used clinically in delivering …

Purpose To characterize solid maltose microneedles and assess their ability to increase
transdermal drug delivery. Materials and Methods Microneedles and microchannels were …

This paper investigates the microneedle-mediated in vitro transdermal delivery of human
IgG as a model protein and demonstrates its applicability to deliver a monoclonal antibody. …

The physical stability of a human growth hormone (hGH) formulation upon exposure to air/water
interfaces (with vortex mixing) and to nonisothermal stress [determined by differential …

Transdermal delivery of peptides and proteins avoids the disadvantages associated with
the invasive parenteral route of administration and other alternative routes such as the …

Effects of calcium silicate (disintegration-promoting agent) and various lubricants on an
optimized β-cyclodextrin-based fast-disintegrating tablet formulation were investigated. Effects of …

Percutaneous absorption is the development of transdermal drug delivery patches, as well
as the treatment of skin disorders. The skin permeability of most drugs is low, but can be …

Microporation involves the creation of micron-sized micropores or microchannels in the skin
which can then allow the transport of water soluble molecules and macromolecules. …