Purpose To enable aggregation rate prediction over a broad temperature range for complex
multi-domain proteins at high concentrations. Methods Thermal unfolding, non-isothermal …

Monte Carlo simulations were performed to study the conformational changes of negatively
charged model peptides dissolved in water adsorbed onto charged surfaces. 8-, 16-, and 20-…

The adsorption of a peptide at solid surfaces is the result of a complex interplay of interactions
between the peptide, solvent, and surface. In this work, Monte Carlo simulations were …

The adsorption of proteins at solid±liquid interfaces is of paramount importance in the
biomedical and biochemical sciences. Protein adsorption on surfaces occurs in implants, …

A kinetic model for the liquid phase oxidation (LPO) of cyclohexane has been derived using
a reaction network based on a consistent free radical mechanism. It was demonstrated that …

The objective of this study was to examine the role of dimension and design of stoppers on
the vapor transfer rate during the lyophilization process. Glass vials (100 cc, 28-mm neck …

Lyophilization or freeze drying of injectable pharmaceuticals is a well-established and
extensively practiced process (1–3). Although used for several conventional and biotechnology-…

Computer simulations can be of great help in detailed studies of the adsorption of peptides
on solid surfaces. Unfortunately, detailed simulations are limited to infinite dilution situations. …

Monte Carlo simulations were performed to study the adsorption of a positively charged
diblock peptide, consisting of five residues each of lysine (LYS) and alanine (ALA), onto …

" The use of enzymes as catalysts is gaining widespread use due to the need to move into
green chemistry approaches. This has been fostered also by the discovery that enzymes can …