Predicting anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones: computational approach using reformed eccentric connectivity index

V Kumar, S Sardana, AK Madan - Journal of molecular modeling, 2004 - Springer
The eccentric connectivity index, which has recently been employed successfully for the
development of numerous mathematical models for the prediction of biological activities of …

Predicting anti-HIV activity of TIBO derivatives: a computational approach using a novel topological descriptor

S Sardana, AK Madan - Molecular modeling annual, 2002 - Springer
A novel highly discriminating adjacency-cum-distance-based topological descriptor, termed
the adjacent eccentric distance sum index, has been conceptualized and its discriminating …

Prediction of anti-inflammatory activity of N-arylanthranilic acids: computational approach using refined Zagreb indices

S Bajaj, SS Sambi, AK Madan - Croatica Chemica Acta, 2005 - hrcak.srce.hr
Zagreb indices M1 and M2 have been refined to significantly reduce their degeneracy. The
refined indices are sensitive to both the presence as well as relative position of the …

[HTML][HTML] Topochemical models for prediction of cyclin-dependent kinase 2 inhibitory activity of indole-2-ones

H Dureja, AK Madan - Journal of Molecular Modeling, 2005 - Springer
The relationship between the topochemical indices and cyclin-dependent kinase 2 (CDK2)
inhibitory activity of indole-2-ones has been investigated. The relationship of topochemical …

Topological models for prediction of pharmacokinetic parameters of cephalosporins using random forest, decision tree and moving average analysis

H DUREJA, S GUPTA, AK MADAN - Scientia Pharmaceutica, 2008 - mdpi.com
The topological indices were used to encode the structureal features of cephalosporins. Both
topostructural and topochemical versions of a distance based descriptor, three adjacency …

Topochemical models for the prediction of lipophilicity of 1, 3-disubstituted propan-2-one analogs

…, V Kumar, S Gupta, AK Madan - Journal of Theoretical and …, 2007 - World Scientific
In the present study, the relationship between the topochemical indices and log P values of
1,3-disubstituted propan-2-one analogs has been investigated. Three topochemical indices, …

Predicting Anti‐HIV Activity of Dimethylaminopyridin‐2‐ones: Computational Approach using Topochemical Descriptors

H Dureja, AK Madan - Chemical biology & drug design, 2009 - Wiley Online Library
In this study, relationship between the topochemical indices and anti‐HIV activity of
dimethylaminopyridin‐2‐ones has been investigated. Three topochemical indices of diverse nature, …

[PDF][PDF] Targeted drug nanoparticles: An emphasis on self-assembled polymeric system

S Gupta, AK Madan - J. Med. Sci, 2010 - researchgate.net
Encouraged by rapid and promising progress in cancer nanotechnology, researchers
continue to develop novel and efficacious nanoparticles for drug delivery. The interest in self-…

Microbial keratitis in Gujarat, Western India: findings from 200 cases

A Kumar, S Pandya, G Kavathia, S Antala… - Pan African Medical …, 2011 - ajol.info
Introduction: The objective of this study was to study the epidemiological characteristics and
the microbiological profile of patients suspected with microbial keratitis in Gujarat. Methods: …

Novel topochemical descriptors for predicting anti-HIV activity

S Gupta, M Singh, AK Madan - 2003 - nopr.niscpr.res.in
The discriminating power of three novel adjacency-cum-distance based chemical topological
descriptors termed as eccentric-adjacency topochemical indices have been investigated to …