User profiles for Auke Bult
a.bulthoogleraar farmacie Verified email at hetnet.nl Cited by 6542 |
Liposome-mediated enhancement of the sensitivity in immunoassays of proteins and peptides in surface plasmon resonance spectrometry
T Wink, SJ van Zuilen, A Bult… - Analytical …, 1998 - ACS Publications
A recently developed liposome sandwich immunoassay for interferon-γ (IFN-γ), to be applied
in microtiter plates, is tailored for surface plasmon resonance (SPR) spectrometry. The …
in microtiter plates, is tailored for surface plasmon resonance (SPR) spectrometry. The …
Analytical techniques used to study the degradation of proteins and peptides: chemical instability
JLE Reubsaet, JH Beijnen, A Bult… - … of pharmaceutical and …, 1998 - Elsevier
Instability of peptides and proteins can be divided into two forms: chemical and physical
instability. Chemical instability is due to modification/alteration of amino acid residues. There are …
instability. Chemical instability is due to modification/alteration of amino acid residues. There are …
Derivatization trends in capillary electrophoresis
JCM Waterval, H Lingeman, A Bult… - ELECTROPHORESIS …, 2000 - Wiley Online Library
This survey gives an overview of recent derivatization protocols, starting from 1996, in
combination with capillary electrophoresis (CE). Derivatization is mainly used for enhancing the …
combination with capillary electrophoresis (CE). Derivatization is mainly used for enhancing the …
A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A
NAMI-A is a novel ruthenium complex with selective activity against cancer metastases currently
in Phase I clinical trials in The Netherlands. The chemical stability of this new agent was …
in Phase I clinical trials in The Netherlands. The chemical stability of this new agent was …
Pre‐, on‐and post‐column derivatization in capillary electrophoresis
…, JCM Waterval, H Lingeman, R Hof, A Bult… - …, 1997 - Wiley Online Library
This survey gives a short overview of the various reagents and procedures that can be used
for pre‐, post‐ and on‐column derivatization in capillary electrophoresis. First there is an …
for pre‐, post‐ and on‐column derivatization in capillary electrophoresis. First there is an …
On‐line sample preconcentration in capillary electrophoresis, focused on the determination of proteins and peptides
T Stroink, E Paarlberg, JCM Waterval, A Bult… - …, 2001 - Wiley Online Library
This overview highlights the possibilities of on‐ or in‐line preconcentration procedures in
combination with a CZE separation, focused on the determination of peptides and proteins. …
combination with a CZE separation, focused on the determination of peptides and proteins. …
On-line multidimensional liquid chromatography and capillary electrophoresis systems for peptides and proteins
T Stroink, MC Ortiz, A Bult, H Lingeman… - … of Chromatography B, 2005 - Elsevier
Peptides and proteins are gaining increasing attention in biosciences and, consequently, in
analysis. This overview highlights the different approaches to couple on-line various …
analysis. This overview highlights the different approaches to couple on-line various …
Interaction between plasmid DNA and cationic polymers studied by surface plasmon resonance spectrometry
T Wink, J de Beer, WE Hennink, A Bult… - Analytical …, 1999 - ACS Publications
A universal and novel strategy for the immobilization of polymers has been developed for
studying the interaction between plasmid DNA and synthetic polymers with surface plasmon …
studying the interaction between plasmid DNA and synthetic polymers with surface plasmon …
On‐line coupling of size exclusion and capillary zone electrophoresis via a reversed‐phase C18 trapping column for the analysis of structurally related enkephalins in …
…, H Lingeman, JCM Waterval, A Bult… - …, 2003 - Wiley Online Library
On‐line coupled analytical techniques can be advantageous in the assay of smaller peptides
in complex biological matrices such as plasma, cerebrospinal fluid (CSF) and tissues. The …
in complex biological matrices such as plasma, cerebrospinal fluid (CSF) and tissues. The …
Penetration of zidovudine into the cerebrospinal fluid of patients infected with HIV
…, PL Meenhorst, JW Mulder, CHW Koks, A Bult… - Aids, 1993 - journals.lww.com
Objective: To investigate penetration of zidovudine (ZDV) into the cerebrospinal fluid (CSF)
of HIV-infected patients for whom a lumbar puncture was indicated. Design: A prospective …
of HIV-infected patients for whom a lumbar puncture was indicated. Design: A prospective …